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In the present study synthesis
2021-02-26
In the present study, synthesis of Bi2MoO6 nanoplates via DNA-templated hydrothermal method has been undertaken. The synthesis was done through the hydrothermal method by means of the reaction of bismuth nitrate pentahydrate (Bi(NO3)3·5H2O) with sodium molybdate dihydrate (Na2MoO4·2H2O) precursor in
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br Materials and methods br Results br Discussion In
2021-02-26
Materials and methods Results Discussion In this study, we have shown that fat body-specific knockdown of the key splicing factors U1-70K and U2AF lead to decreased triglyceride storage phenotypes in larvae. Additionally, there was no accompanying defect in glycogen storage observed in thes
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As the COMT enzyme is primarily
2021-02-26
As the COMT enzyme is primarily related to prefrontal dopamine degradation (e.g., Yavich et al., 2007), the present study supports the notion that prefrontal dopamine modulates retention of fear extinction rather than within-session extinction (Abraham et al., 2014). Consistent with other studies we
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These data indicate that in the context of the
2021-02-26
These data indicate that, in the context of the N-terminal 42 amino acids of p53, threonine 18 is a substrate for phosphorylation by CK1 as mediated by prior phosphorylation of serine 15. To determine whether this is a property of full length p53, GST-p53 fusion proteins comprising the full length p
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In rodent models the loss
2021-02-26
In rodent models, the loss of estrogens through ovariectomy has been shown to promote the development of intracranial aneurysms. Conversely, the administration of an 7α,25-dihydroxy Cholesterol receptor beta agonist restores its protective effect, but is abolished with the introduction of a nitric
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The presence of a vicious cycle
2021-02-26
The presence of a “vicious cycle” established between tumor proliferation and paratumor osteolysis plays a crucial role in the development of primary bone tumors [53]. Cancer cells produce soluble factors that activate directly or indirectly via osteoblasts, osteoclast differentiation and maturatio
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EBI and its ligand s EBI
2021-02-26
EBI2 and its ligand(s) EBI2 was found in a screen of upregulated genes in human B cells upon infection with EBV [1]. EBI2 is a G-protein (Gαi type) coupled receptor [2] but as long as 18 years after its discovery the nature of its ligand remained undisclosed. With the help of transfected cell lines
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Our previous studies indicate that EBI is involved
2021-02-26
Our previous studies indicate that EBI2 is involved in the regulation of pro-inflammatory responses and inter-cellular communication under pathophysiological conditions such as LPS challenge (Rutkowska et al., 2016b). The data showed that media taken from LPS stimulated astrocytes induces macrophage
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br Methods br Results br Discussion Skin biopsy and
2021-02-26
Methods Results Discussion Skin biopsy and microneurography have both been described as useful tools in the diagnosis of PAN, directly identifying peripheral sympathetic fibers without the mediation of specific cyclohexamide organs (Donadio et al., 2005, Donadio et al., 2012a, Donadio and L
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In most cases patients will not
2021-02-25
In most cases, patients will not present immediately after SM exposure because SM-induced clinical symptoms typically occur after a latency period of several hours [8], [9], [10]. When they do present, the detection of free, unbound alkylating agent is highly unlikely. For this reason, available rap
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br Structure of ketosteroid dehydrogenase Overall
2021-02-25
Structure of 3-ketosteroid Δ1-dehydrogenase Overall fold — High-resolution crystal structures of Δ1-KSTD are currently available for the Δ1-KSTD1 isoenzyme from R. erythropolis SQ1 [30]. The Δ1-KSTD1 molecule has an elongated shape, and consists of two domains, an FAD-binding domain and a catalyt
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Pulmonary fibroblasts can regulate the wound healing
2021-02-25
Pulmonary fibroblasts can regulate the wound healing process by secreting and processing extracellular matrix (ECM), chemokines, and cytokines. However, persistent and atypical fibroblast proliferation can result in ECM accumulation and may trigger the onset or development of pulmonary fibrosis [[17
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br Acknowledgements br This work was
2021-02-25
Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Grant No.: 30260088) and the prophase research for National “973” Project of China (Grant No.: 2007CB116203). The DNA sequences of Hbvp1 and the Hbvp1 promoter were deposited in GenBank, an
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Progesterone mg In the present study we
2021-02-25
In the present study, we combined activity-based protein profiling, biochemical and genetic approaches to identify the PLCPs involved in the sphingolipid pathway leading to plant PCD. By using Arabidopsis Progesterone mg and leaves, we demonstrate that this sub-class of plant proteases is activated
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In the last and the
2021-02-25
In the last and the most challenging part, three mixtures were selected to evaluate the reliability of the presented correlation and the CPA model. For Athabasca bitumen, Amani et al. [25] measured the experimental data at very high temperatures compared to the thermal recovery range up to 644 K (ne
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