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br Materials and methods br Results
2021-06-15
Materials and methods Results Discussion Approximately 90% of pulmonary emphysema causes are related to smoking and its progression in patients and are characterized by severity levels [5]. Experimental models using CS to induce emphysema are widely used because they resemble the emphysema
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br Expression and Tissue Functions of DDRs The DDRs
2021-06-15
Expression and Tissue Functions of DDRs The DDRs are widely expressed in different tissues, both during development and in adult organisms. DDR1 mRNA is found in many tissues in mice and humans, with high levels in brain, lung, kidney, spleen, and placenta (Di Marco et al., 1993, Johnson et al.,
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In general cellular senescence is considered
2021-06-15
In general, cellular senescence is considered a programmed response to stress that can be activated by oxidative stress, irradiation or action of substances or drugs. These stressors cause DNA damage and, through the action of specific proteins (p53 and p21), lead to cell senescence (di Fagagna, 200
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Ubiquitination is a covalent attachment of amino acid
2021-06-15
Ubiquitination is a covalent attachment of 76 amino hyPerFUsion™ high-fidelity PCR Kit ubiquitin molecules to target proteins, either as single moieties (mono-ubiquitination) or as poly-ubiquitin chains of different structures, formed through isopeptide bonds between specific lysines of one ubiquiti
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br Methods br Results br Discussion Skin biopsy and microneu
2021-06-15
Methods Results Discussion Skin biopsy and microneurography have both been described as useful tools in the diagnosis of PAN, directly identifying peripheral sympathetic fibers without the mediation of specific rho kinase inhibitor organs (Donadio et al., 2005, Donadio et al., 2012a, Donad
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Currently it is not known
2021-06-15
Currently, it is not known if drought induces changes in the cysteine protease Betaine of soybean nodules. The available annotation of the soybean genome, in Phytozome (www.phytozome.net) has identified 706 C1 cysteine protease sequences and 75 C13 cysteine proteases. We have previously reported ex
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Because flavonoids are widely considered to
2021-06-15
Because flavonoids are widely considered to contribute to health benefits in humans, including anti-inflammatory, antibacterial, antiviral, anticancer, antiplatelet properties, and free radical scavenging capacity (Xiao et al., 2011), efforts have frequently been made to increase their bioavailabili
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Moreover a ligand for fusin has recently been
2021-06-15
Moreover, a ligand for fusin has recently been found: the lymphocyte chemoattractant stromal-derived factor-1 (SDF-1) binds to CHO EG00229 transfected with fusin and promotes secondary messenger production (Bleul et al., 1996; Oberlin et al., 1996). A new name, CXCR-4, has been proposed for the rece
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Introduction The carnitine choline acyltransferase
2021-06-11
Introduction The carnitine/choline acyltransferase family is a family of enzymes that play diverse roles, ranging from (the regulation of) Valproic acid synthesis and fuel metabolism in mitochondria and peroxisomes to the generation of the neurotransmitter acetylcholine. In mammals, this family co
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On close inspection the pattern shows
2021-06-11
On close inspection, the pattern shows large areas of very low point intensity where hardly any trees can be found. Anecdotal knowledge reveals that these regions are covered by a swamp, where the tree species is known to be very unlikely to grow, independent of local soil covariates and topography.
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Tinnitus Met carriers with severe hearing
2021-06-11
Tinnitus Met carriers with severe hearing loss perceive their tinnitus as being louder, which is associated with increased activity in the PHC, increased PHC→pgACC connectivity, as well as decreased pgACC→PHC connectivity. This indicates that Met carriers with severe hearing loss have increased tinn
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The modes of action of insecticides are classified by
2021-06-11
The modes of action of insecticides are classified by the Insecticide Resistance Action Committee (IRAC) [6]. In this classification, a large proportion of insecticides are categorized as nerve- and muscle-targeting insecticides, which encompass GABACl antagonists (Group 2) and GluCl allosteric modu
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LP a levels are lowered by combined
2021-06-11
LP(a) levels are lowered by combined oral hormone therapy [80], [81], [82], [83], [84], whereas for most studies using transdermal HRT little or no changes have been observed [85], [86], [87]. Oral versus transdermal administration In general most markers are influenced in a similar way by oral
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Our previous studies have shown that
2021-06-11
Our previous studies have shown that in a preimplantation mouse embryo the proportion of inner to outer cells (i.e. precursors of ICM and TE, respectively) is regulated by a different frequency of differentiative cell divisions at the 8- and 16-cell stages. Low number of inner blastomeres generated
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melanotropin The transcription factor CREB has been extensiv
2021-06-11
The transcription factor CREB has been extensively studied for its role in hippocampus-dependent learning and memory (West et al., 2002, Lonze and Ginty, 2002). Previous research has demonstrated that the phosphorylation of CREB at Ser133, performed by the ERK1/2 signaling pathway, initiates a casca
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